Friday 1 April 2016

Introduction
Computer
A computer is a device that can be programmed to carry out a set of arithmetic or logical operations automatically according to instructions written in a software.
Conventionally, a computer consists of at least one processing element, typically a central processing unit (CPU), and some form of memory. The processing element carries out arithmetic and logic operations, and a sequencing and control unit can change the order of operations in response to stored information.
Why computer is important in the field of Pharmacy…?
The computer has become a very common tool in all areas of science and technology. With the proliferation of the Internet and the developments in computer technology and manufacturing, the ratio of price to performance of computers continues to decrease. This has resulted in the development of number of computer applications.
In Pharmacy field, effective use of computers started from 1980. Since then there is great demand of computers in pharmacy field. The field of pharmacy has immensely benefited by the use of computer and will continue to benefit as the pharmacist's gain more familiarity with computer. Some of the important areas where computers are useful are new drug discovery, drug design, analysis, manufacturing of drugs and hospital pharmacy. Other than these, computers helps pharmacist collaborate with other professionals, which is very essential in today's research work.
It also provides solutions for time consuming manual task. Various hardware and softwares have been developed without which drug discovery, designing, manufacturing and analyzing would become virtually impossible. Further development is still in progress which will make pharmacist's job easier.
The more important fact is that they will enable us to discover new drugs for the complete care of dangerous of diseases like aids, cancer etc. and reduce the cost of production of drugs for diseases which are easily cured.
Computers are also useful for hospital pharmacist and in telemedicine. A lot has been done and a still has to be done for improving the computer facilities for pharmacist.
Here are some important applications of computer in pharmacy.

Applications of computer in Pharmacy

1.      Prescription filling: Patient name, doctor name, drug name, quantity, prescription number; prints the label, calculates the price, discount, etc.
2.      Prescription Refilling: Pharmacist enter data regarding the prescription if data not available to avoid any warning message appears if the prescription is out of data
3.      E_ Prescribing E-prescriptions are computer-generated prescriptions created by healthcare provider and sent directly to pharmacy. E-prescriptions are sent electronically through a private, secure, and closed network.
E-prescriptions are:
Ø  Fast - Your prescription arrives at your pharmacy before you leave your doctor’s office.
Ø  Convenient - You don’t have to make that extra trip to drop off your prescription at the pharmacy.
Ø  Legible - There is no handwriting for the pharmacist to interpret.
Ø  Economical - makes it easier for your doctor to prescribe the most cost effective medication based on your insurance coverage.
4.      Prescription Processing:  Prescription processing is invariably one of the main activities going on within a pharmacy on a day-to-day basis, and computers are used to make this process more reliable and efficient.
Ø  Both the customer service side of pharmacy operation and the dispensing aspect are today carried out through the use of computing systems.
Ø  Pharmacy computers also handle customer service activities such as sales and cash handling within the retail operation.
5.      Patient Counseling:  Pharmacist can print counseling handout, prescription label and invoice.
Ø  Also handout contains any information the patient might need to know regarding precautions or side effects of the medication
6.      Patient Profile: Pharmacist can updated patient profile whenever a new prescription is filled
Ø  Also if the patient might have any symptoms like allergies, it should be added to patient profile
7.      Drug-drug interactions:  There is program regarding this point, this provided from many vendors offer programs for drug interaction. The pharmacist must check the patient’s  profile and  prescription to determined if there is interaction
8.      Tax and Insurance Reports: This point must be asked to do, so the pharmacist can print the data for medical expense. Listing the information patient needs to file tax return or insurance claims
9.      Third Party Programs: The pharmacist enters the patient’s identification number for verification and updating, thereby reducing the possibility for error and often speeding the payment procedure
10.  Nursing Home Reports: Some information must be added by nursing home administrators, including physician order sheet, unit dose filling profile, medication administration records, and consultant pharmacist evaluation  
11.  Accounts Receivable:  This offer from vendor of computerized data processing. In most systems the account can be aged may 30 or 60 or day
12.  Pricing Formulas: The program is available for select specific formulas for pricing medication. It include stander structure for pricing
13.  Control Substance Records: This for controlled substance items that order during period, along with quantities and dosages
14.  Stock movement reports: This depend on how much of drugs taken from previous inventory and this allowing to pharmacy manager to minimizing the actual inventory investment
15.  Merchandise Control Reports: This point to know the goods move fast or slow, also provide information for pricing decisions and judges for entire store's performance
16.  Electronic Order Entry: Now the wholesalers provide for other pharmacies interface with their central computers to order new medications.
Ø  Also pharmacy’s employees take inventory of the shelf stock using optical scanner to read and record product codes and quantities
17.  Permanent Shelf Labels: In-addition, wholesalers provide shelf labels containing the product description, item number, size, fine-line code, universal product code bars and other information
18.  Customized Price Stickers: Wholesalers supply price stickers, also sticker include other information (quantity ordered item number, cost and date of merchandise order)
19.  Daily and Monthly Log: Computer program can provide a pharmacy with a timely, precise review of prescriptions broken out into prescription number, patient type, gross profit margins and other information.
20.  Management Reports: There is a lot of different types of reports can help the pharmacy manager in his practice and his business. These like, accounting, payroll administration, cost and financial  analysis market analysis, budgeting, sales forecasting and investment analysis
21.  Communication: Computers are used within pharmacies to facilitate communication.
Ø  From email to other Internet-based messaging systems, online communication allows pharmacists and other pharmacy staff to keep in contact both within their own organization and within the professional community.
Ø  Some pharmacy companies have their own Intranet systems for internal communications over the Internet.
22.  Information: Having access to the Web via pharmacy computers is something that has enhanced the ability of pharmacists to carry out their duties to a higher standard.
Ø  As well as giving the pharmacy staff access to the vast store of information that is available on the Internet, including those on specialist pharmacy resources, the
Ø  Internet connects pharmacists to their peers on a global scale.
Ø  Professional communities for pharmacists operate on-line, creating an atmosphere that is conducive to professional development.
23.  Databases: Computer databases for information about medicines, and medical treatment in general, are used within pharmacies.
Ø  These database systems allow pharmacy staff to find out information about any potential conflicts or health-care problems in a prescribed treatment, as well as information about the details of any particular medicine the pharmacist needs to know more about.
Ø  This information may include ingredients and potential effects as well as research and scientific data.
24.  Patient Management: Health care clinicians and administrators alike are showing enthusiasm for one of the medical field's newest technological trends: patient information management systems.
Ø  These electronic systems serve as a database for storing patient files.
Ø  Information can be easily added, changed, deleted, printed or audited by clicking a few buttons on the computer.
Ø  Pharmacists do not have to store or carry around health records any longer, because all they need is access to a computer or laptop to pull up patient information.
25.  Scheduling: When a patients call a pharmacy to make an order, the representative who answers the phone can schedule them through the use of a computer appointment scheduling system.
Ø  These electronic systems allow front office staff to add, delete or change appointments with the click of a mouse.
Ø  If there is more than one order, schedules can be sorted by Pharmacist, as well as be color-coded to indicate it when the order be available.
26.  Error Prevention: Pharmacy computer systems can help to prevent errors in medication, potentially saving lives and generally preserving the health of patients.
Ø  As well as checking medicines and combinations of medicines, these systems can in some cases check on patient information.
Ø  The availability of such systems varies across the different geographical areas, but in some cases pharmacy computers are able to check on prescribed medicines with specific reference to a patient and their overall health-care picture.
27.  Medical Claims: Computers are what health care companies are using to submit, review, process and pay medical claims, according to a 2006 article by the Healthcare Financial Management Association.
Ø  Health technology trends indicate that more and more companies are relying on computers to submit their claims, rather than submitting them via hard copy, because computers expedite the process.
Ø  Information management engineers have created systems and technology tools that make the claims process of the medical field more efficient and easy to use.
28.  Computer and medical education: Computers have revolutionized the way education is handled in the today’s world.
Ø  In medical education, computers are particularly useful because there is such a need for learning and presenting large amounts of data, getting and comparing accurate study and test results, and effectively monitoring patients..
29.  Miscellaneous services: The pharmacy manager can take advantage of numerous miscellaneous services offered by wholesalers.

Ø  These services include some reports regarding new items, price changes, special offers and special discounts.
Special areas of pharmacy required computer:

A.    USE OF COMPUTERS IN RETAIL PHARMACY SHOP
                  Computers are used by community pharmacist for various functions. Some accounting functions are like;
·         preparation of prescription label
·         providing a receipt for patient
·         generation a hard copy record of transactions
·         calculating total prescription cost
·         automatically ordering the low quantity products via electronic transitions
·         preparation of annual withholding payrolls.
·         Managerial functions include generation of multiple sales analysis for a day, month, weak and to date for number of prescriptions handled and amounts in cash.
·         Estimation of profits and financial ration analysis
·         calculation of number of prescription handled per unit time
·         printing of billing and payment details
·         purchasing and inventory control in retail pharmacy.
For gathering of information international data banks are available such as World standard drug database, Drug bank, MEDLARS (Medical Literature Analysis and Retrieval System) and DIALOG. MEDLARS are a computerized biomedical bibliographic retrieval system.

B.     HOSPITAL AND CLINICAL PHARMACY
Hospital pharmacy is division of hospital which monitors on the receiving and allotment of drugs and medicines and professional supplies, stores them and dispenses to in-out patients.
Patient record maintenance is vital job in hospitals but with the help of computers, data can be maintained easily and also updated time to time.For this purpose, periodic or perpetual inventory control systems may be adapted
·         Softwares like Microsoft Excel are useful in maintenance of all type of numerical data.
·         Clinical pharmacist may use computers for therapeutic drug monitoring; which are very potent and having very narrow therapeutic.
·         Computer program are designed to calculate drug dosage to suit individual patients need.
·         drug interactions may be screened by using programs like MEDIPHOR (monitoring and Evaluating of Drug interactions by a pharmacy oriented reporting) and PAD(Pharmacy Automated Drug Interaction Screening).
C.    COMPUTER ADDED DRUG DESIGN
Drug design, also sometimes referred to as rational drug design, is the inventive process of finding new medications based on the knowledge of the biological target. This type of drug design can be assisted by computer softwares
Various types of softwares are available,
·         AutoDock (The Scripps Research Institute)
·         CombiBUILD (Sandia National Labs)
·         DockVision (University of Alberta)
·         LIGPLOT (University College of London)
·          SITUS (Scripps Research Institute)
·         DOCK (UCSF Molecular Design Institute
·         Bio-Suite (Tata Consultancy Services Ltd.), Maestro, Macro Model 5.5, Delphi etc.

D.    COMPUTERS IN MANAGEMENT OF CLINICAL TRIALS
Clinical trials are the important part of current drug development which provides information about risk and benefits of any medication. Data collection and management are very crucial in clinical trials.
The astonishing advancement in computer hardware and software technology has had tremendous impact on clinical trials data collection and management
·         Softwares can be used for the trial database, data collection/data entry, randomization, registration, study management tools, and statistical analysis.
·         Communication between volunteer and physician is very important. Various computer assisted methods can be utilized for communication purpose like;
 e-mail
 Web-sites
 Video conferencing

E.     COMPUTERS IN PUBLICATION
Publication of research work is an important aspect in any field and pharmacy field is not exception to it. Publishing research is a vital element of researcher’s professional life. However, writing is not every researcher’s desired activity and the difficulty of getting a paper published can be nerve-wracking. However use of computers in writing and editing makes it very effortless and versatile to prepare and publish article. Computer may be required at the different stages for the author, publisher and reviewer.



F.     E-clinical softwares
E-clinical softwares consist of integrated suits of application s that support clinical research process, including various ways of data collection, data entry, remote data capture, batch data load. These suites enable to quickly and easily design studies, capture clinical data, some examples of e-clinical softwares are
1. Oracle clinical V4i® from Oracle Corporation.
2. Data LabsXC® from Data labs, Inc.
3. Trial master® from Omnicomm systems.
4. Cliniplus® Data management from DZC software solution, Inc.
5. Openclinica by Akaza research (Cambridge, MA)

Pharmacokinetic analysis is basically carried out to get information on renal clearance, volume of distribution, metabolic deposition, absorption and multiple dosing of drug. This type of analysis can be carried out by using different softwares.
There are different approaches to pharmacokinetics using differential equations with the help of softwares.
Ø  NONLIN is the software which allows you to perform statistical regression analyses to estimate the values of parameters for linear, multivariate, polynomial, and general nonlinear functions
Ø  KINPAK is software used to obtain Area under curve (AUC), Peak plasma concentration (Cmax) and peak plasma time (tmax)
Ø  ESTRIP and STRIPACT are programs which are also used for mathematical analysis. These softwares help in therapeutic drug monitoring of patient.

COMPUTER SOFTWARE USED IN PHARMACY
1.   WinPharm:
2.   Pioneer RX
3.   HBS Pharmacy Software
4.   Arteb Pharmacy Solution e.t.c
Standard pharmacy software features should include:
·         User friendly input and recall of patient, drug and prescription information
·         HIPAA and regulatory compliance (including DEA reporting, FDA required MedGuides)
·         Full prescription management
·         Complete third-party claims submissions including adjudication (V5.1, etc)
·         Failsafe features for safety and accuracy
·         On-line reconciliations
·         Drug-file updates
·         Tailored labels
·         A/R management
·         Inventory management
·         Electronic wholesaler ordering
·         Bar code scanning
·         Signature capture
·         E Prescribing
·         Auto Dr fax
·         Complete and accurate drug interaction and other databases
·         Interfaces for POS, IVR, Automatic Dispensing Systems, reconciliation systems and other important third party products and services
Ultimately, the right software will allow you make better business decisions and give you an edge in the market. A representative financial model will help you evaluate the financial impact of pharmacy management software on your business.
USE OF INTERNET IN PHARMACY

Internet is collection of huge data. And this data is available for us in just a one click. Internet is useful tool in literature survey. Books are also available on the internet. Various research journals can be easily accessed via internet.
      There are number of web-sites which are related to pharmacy field are as follows;
Organization representing America's pharmaceutical research companies provides details of drug development, industry news, and health guides.
Created to facilitate interaction among healthcare professionals on specific topics which includes discussion of cases, research and other relevant issues.
This is official web-site of ASTRA pharmaceuticals which produces medications for respiratory tract, cardiovascular and gastrointestinal diseases, and for pain relief. Includes press releases.
Company principally engaged in developing genetically-engineered human pharmaceuticals. With career advice, and drug information.
Develops pharmaceuticals mostly for the treatment of genetic disorders. Includes a listing of the major drugs and their uses.
Company that specializes in biotechnology and health care products. With career, product, and services information.
Find out about research projects and career opportunities at this Pfizer pharmaceuticals. Includes health education and pharmaceutical advice section.
Roche produces pharmaceuticals and products for treatment of HIV, obesity and cardiac conditions. Offers news and company information.

 Listing of international pharmaceutical regulatory bodies including the US Food and Drug Administration.
Ø  http://www.druginfonet.com
Drug information, disease information, Ask the Expert, Pharmaceutical Manufacturer Information, Healthcare news and information, Medical References / libraries.
Ø  http://www.fda.gov/default.htm
Useful for checking adverse reaction reports for dietary supplements and drug interactions
Ø  www.ijpc.com
Alphabetical Index of formulations found in the International Journal of Pharmaceutical Compounding. Specialty articles on compounding
Ø  http://www.pharmainfo.com
Pharmaceutical News, Pharmaceutical Articles, and Pharmaceutical blogs
Ø  www.fda.gov/cvm/
Searchable listing provides facts and figures on all animal drug products approved by the FDA.
Ø  www.aaps.org
Information on officers, activities and membership from the American Association of Pharmaceutical Scientists
Ø  http://www.sciencedirect.com
Contains research and review articles related to pharmacy field

Advantages & Disadvantages of Computers in a Local Pharmacy
Advantage: Accessibility
      In a pharmaceutical setting, if the pharmacist wants to look up a patient's prescription history or fill/renew a prescription, he can do it in seconds, simply by entering the customer's name.
      This is faster than the traditional way, which consisted of riffling through filing cabinets until the customer's folder was found.
Advantage: Customer Time Savings
      help customers choose over-the-counter, or OTC, drugs. For example, according to an April 2008 ABC article "Computer Kiosks Aid Pharmacy Needs," kiosk-like computers have been launched in pharmacies that allow customers to plug in their signs and symptoms.
      The computer will then recommend which OTC medicine might be best.

Advantage: Improving Patient Compliance
      Community pharmacies can use their computer systems and direct patient access to deliver a quality and breadth of patient care unavailable anywhere else.
      Pharmacy computer systems are already being used extensively for Electronic Data Interchange (EDI) with other business and trading partners.
Disadvantage: Hacking
      One disadvantage of using computers anywhere, let alone in a local pharmacy, is that they're susceptible to being hacked.
      According to the Mount Airy News article "Local Pharmacy Computers Hacked," most hackers target pharmacies to steal data for financial gain or for malicious purposes such as spreading viruses.
      However, a potentially more serious threat is acquiring the personal information of customers, which is data that is typically stored in such computers.
Disadvantage: Training
      A downside to computers is that when such technology is introduced into a work environment, the employees there need to be able to properly use it. This requires training, which can take time and cost money.
      If employees aren't properly trained to use the equipment, then the enhanced efficiency of using the technology is no longer present.